BC 362- Medical Biochemistry

Lecture: T, Th 9:30 - 10:45 AM
(Keyes 105)

Discussion: Fr 12:00-12:50 PM
(Lovejoy 215)

Instructor:
Julie T. Millard

Keyes 304, x5757



Course Objectives
This is an intensive course that provides in-depth exposure to the principles of biochemistry most important to an understanding of health and disease. Major topics include the functions and interactions of the major classes of biomolecules and the transduction and storage of cellular energy (metabolism).

Attendance Policy
Attendance at every class meeting is expected. Unexcused absences from class could result in a reduction of your grade. Please keep in mind that only Prof. Millard can determine what constitutes an excused absence for this course.

Course Materials:

Week 1 Powerpoint: Intro, Water, and Buffers

Week 2 Powerpoint: Amino Acids

Week 2 Powerpoint: Peptides and Proteins

Week 3 Powerpoint: Hemoglobin

Week 4 Powerpoint: Enzyme Kinetics

Week 4 Powerpoint: Enzyme Inhibition

Week 5 Powerpoint: Enzyme Mechanisms

Week 5 Powerpoint: Carbohydrates

Week 6 Powerpoint: Lipids and Membranes

Week 7 Powerpoint: Introduction to Metabolism

Week 8 Powerpoint: Glycolysis

Week 8 Powerpoint: TCA

Mr. Colby Case Study

Week 9 Powerpoint: ETC

Week 9 Powerpoint: Ox Phos

Week 10 Powerpoint: Gluconeogenesis

Week 10 Powerpoint: Other Carb Pathways

Week 11 Powerpoint: Fat Metabolism

Week 12 Powerpoint: Amino Acid Metabolism

Week 12 Powerpoint: Integration of Metabolism



Dr. Antoniello's Powerpoint on pH and Medicine

Dr. Antoniello's Powerpoint on Metabolic Disorders

Useful Links:

Syllabus

ExPASy (The Expert Protein Analysis System proteomics server of the Swiss Institute of Bioinformatics)

Online Mendelian Inheritance in Man

Sample Exam 1

Key to Sample Exam 1

Sample Exam 2

Key to Sample Exam 2

Solutions to First Exam

Solutions to Problem Set 7

Limited Solutions to Problem Set 8

Solutions to Extra Glucose Problems

Solutions to Second Exam

Schedule for Case-Study Presentations

Schedule of Metabolic Disorders Presentations


Metabolic Disorders Presentations:

von Gierke Disease

Andersen Disease

Fanconi-Bickel Syndrome

Hurler Syndrome

Niemann-Pick Disease

Tay Sachs Disease

Fabry Disease

Trimethylaminuria

MSUD