BC 362- Medical Biochemistry

Lecture: T, Th 9:30 - 10:45 AM
(Keyes 105)

Discussion: Fr 9:00- 9:50 (section A, Lovejoy 213) or 12:00-12:50 (section B, Lovejoy 215)

Julie T. Millard

Keyes 304, x5757

Course Objectives
This is an intensive course that provides in-depth exposure to the principles of biochemistry most important to an understanding of health and disease. Major topics include the functions and interactions of the major classes of biomolecules and the transduction and storage of cellular energy (metabolism).

Attendance Policy
Attendance at every class meeting is expected. Unexcused absences from class could result in a reduction of your grade. Please keep in mind that only Prof. Millard can determine what constitutes an excused absence for this course.

Course Materials:

Week 1 Powerpoint: Intro, Water, and Buffers

Week 2 Powerpoint: Amino Acids and Peptides

Week 2 Powerpoint: Primary and Secondary Protein Structure

Week 3 Powerpoint: Globular Proteins

Week 4 Powerpoint: Enzyme Kinetics

Week 4 Powerpoint: Enzyme Inhibition

Week 5 Powerpoint: Enzyme Mechanisms

Week 5 Powerpoint: Carbohydrates

Week 6 Powerpoint: Lipids and Membranes

Week 7 Powerpoint: Overview of Metabolism

Week 8 Powerpoint: Glycolysis

Week 8 Powerpoint: TCA

Week 9 Powerpoint: Electron Transport

Week 9 Powerpoint: Ox-Phos

Week 10 Powerpoint: Gluconeogenesis

Week 10 Powerpoint: Other Carb Pathways

Week 11 Powerpoint: Fat Catabolism

Week 12 Powerpoint: Fat Anabolism

Week 12 Powerpoint: Nitrogen Metabolism

Week 13 Powerpoint: Integration of Mammalian Metabolism

More Metabolic Disorders Presentations:
Propionic Acidemia
Dihydrolipoamide Dehydrogenase Deficiency
Maple Syrup Urine Disease
ASAL Deficiency
Useful Links:


ExPASy (The Expert Protein Analysis System proteomics server of the Swiss Institute of Bioinformatics)

Online Mendelian Inheritance in Man

Sample Exam 1

Key to Sample Exam 1

Sample Exam 2

Key to Sample Exam 2

Schedule for Case-Study Presentations

Case Study Rubric

Limited Solutions to Problem Set 4

Limited Solutions to Problem Set 5

Solutions to Quiz 4A

Solutions to Quiz 4B

Solutions to Exam 1

Limited Solutions to Problem Set 6

Limited Solutions to Problem Set 7

Limited Solutions to Problem Set 8

Solutions to Exam 2

Limited Solutions to Problem Set 10

Schedule of Metabolic Disorders Presentations

Metabolic Disorders Presentations:
McArdle's Disease
Pompe Disease
Gaucher's Disease
Cystathionine beta synthase defect
Tyrosinase deficiency