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  • Andrea Tilden
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Andrea Tilden

Title

The Leslie Brainerd Arey Associate Professor of Biosciences

Department

Biology

Information

  • (207) 859-5743
  • [email protected]
  • 207-859-5705
  • Arey Life Sciences Building

Address

5743 Mayflower Hill Waterville, Maine 04901-8853

Current Courses

CRS Title Sec
BI100 Navigating the World of STEM Research A
BI163 The Cellular Basis of Life D
BI371 Applied Biomedical Genomics A

Areas of Expertise

  • Genomics and Bioinformatics

  • Neurobiology

  • Animal physiology

  • Endocrinology

Current Research

Comparative Genomics: Eukaryotic Evolution: A trademark of the eukaryotic genome is the abundance of noncoding genetic material in the form of introns and intergenic expanses that can constitute the vast majority of a genome (~99% in humans). While some of this material has known functions, much is functionally questionable. The origins of this noncoding material are mysterious and an area of speculation and debate. My lab uses computational tools to analyze the evolutionary origins and trajectories of intron/exon structure to make predictions about a) the nature of intron invasion, b) resulting influences on gene structure, and c) implications for eukaryogenesis, multicellularity, and cellular differentiation. Gene Duplications: Gene duplications can be a source of evolutionary novelty. These duplications can assume gain-of-function, subfunctional, or neofunctional roles, or they may become pseudogenes. My lab is studying duplications using expression assays and computational tools that can predict these fates.

Colby College
4000 Mayflower Hill
Waterville, ME 04901 207-859-4000
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