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Julie Millard

Title

The Dr. Gerald and Myra Dorros Professor of Chemistry

Department

Chemistry

Information

Address

5757 Mayflower Hill Waterville, Maine 04901-8853

Current Courses

CRS Title Sec
BC197 Potions, Poisons, and Perfumes: Medicinal Plants of Great Britain A

Julie received her B.A. in Chemistry and Neuroscience at Amherst College and her Ph.D. in Biochemistry at Brown University before working as a post-doctoral Research Fellow at the University of Washington and a Dreyfus Teaching and Research Fellow at the University of Richmond. Prof. Millard has taught Biochemistry, Exercise Physiology, General Chemistry, and chemistry for non-majors at Colby since 1991 and is currently teaching a W1 course called The Science of Crime. Her research is in the field of DNA-drug interactions, investigating how some small molecules cause cancer whereas others act as anti-cancer drugs. Many of Prof. Millard’s students have appeared as co-authors on publications appearing in such journals as Biochemistry. She was named a Henry Dreyfus Teacher-Scholar in 2006 and a Fellow of the American Association for the Advancement of Science in 2016, and her research has been funded by the American Chemical Society, Research Corporation, and the NIH. She is also the author of a textbook for non-majors called Adventures in Chemistry. Click here for more information on Prof. Millard.

Education

Ph.D., Biochemistry, Brown University
B.A., Magna Cum Laude, Chemistry and Neuroscience, Amherst College

Areas of Expertise

  • Primary research focus: Implications of caffeine metabolism genotype and phenotype
  • Secondary research focus: Interaction of DNA and anti-cancer drugs
  • Additional interests: DNA profiling and CODIS

Personal Information

  • Fellow of the American Association for the Advancement of Science
  • Learn more on Professor Millard's website.

Publications

Colby Publications Only Listed Below:

  • 30. Genotype and Phenotype of Caffeine Metabolism: A Biochemistry Laboratory Experiment (2018) Julie T. Millard, Tenzin Passang, Jiayu Ye, Gariel M. Kline, Tina M. Beachy, Victoria L. Hepburn, and Edmund J. Klinkerch, Journal of Chemical Education 95, 1856- 1860.
  • 29. Changes in Apoptotic Gene Expression Induced by the DNA Cross-Linkers Epichlorohydrin and Diepoxybutane in Human Cell Lines (2018) Vanesa L. Silvestri and Julie T. Millard. Data in Brief 19, 932-935.
  • 28. Cross-linking by epichlorohydrin and diepoxybutane correlate with cytotoxicity and lead to apoptosis in human leukemia (HL-60) cells (2018) Phuong M. Le, Vanesa L. Silvestri, Samuel C. Redstone, Jordanne B. Dunn, and Julie T. Millard. Toxicology and Applied Pharmacology 352, 19-27.
  • 27. Polymerase Bypass of N7-Guanine Monoadducts of Cisplatin, Diepoxybutane, and Epichlorohydrin (2018) Jiayu Ye, Caitlin Farrington, and Julie T. Millard, Mutation Research, Fundamental and Molecular Mechanisms of Mutagenesis 809, 6-12.
  • 26. Case-Study Investigation of Equine Maternity via PCR-RFLP: A Biochemistry Laboratory Experiment (2013) Julie T. Millard, Edward Chuang, James S. Lucas, Erzsebet E. Nagy, and Griffin T. Davis, Journal of Chemical Education 90, 1518-1521.
  • 25. Diepoxybutane Interstrand Cross-Links Induce DNA Bending (2012) Julie T. Millard, Erin E. McGowan, and Sharonda Q. Bradley, Biochimie 94, 574-577.
  • 24. DNA Profiling of Convicted Offender Samples for the Combined DNA Index System (2011) Julie T. Millard, Journal of Chemical Education 88, 1385-1388.
  • 23. Enhancing Your Professional Presence (2010) Julie T. Millard, In Mentoring Strategies to Facilitate the Advancement of Women Faculty; Karukstis, K., Gourley, B. L., Rossi, M., Wright, L. L., Eds; ACS Symposium Series; American Chemical Society: Washington, DC.
  • 22. Integrating Work and a Personal Life: Aspects of Time and Stress Management for Senior Women Science Faculty (2010) Julie T. Millard and Nancy S. Mills, In Mentoring Strategies to Facilitate the Advancement of Women Faculty; Karukstis, K., Gourley, B. L., Rossi, M., Wright, L. L., Eds; ACS Symposium Series; American Chemical Society: Washington, DC.
  • 21. DNA Interstrand Cross-Linking Activity of (1-Chloroethenyl)oxirane, a Metabolite of β-chloroprene (2010) Brian A. Wadugu, Christopher Ng, Bethany L. Bartley, Rebecca J. Rowe, & Julie T. Millard, Chemical Research in Toxicology 23, 235-239.
  • 20. Television Medical Dramas as Case Studies in Biochemistry (2009) Julie T. Millard, Journal of Chemical Education 86, 1216-1218.
  • 19. Crime Scene Investigation in the Art World: The Case of the Missing Masterpiece (2009) Katharine J. Harmon, Lisa M. Miller, & Julie T. Millard, J. Chem. Educ. 86, 817-819.
  • 18. Quantitative PCR analysis of diepoxybutane and epihalohydrin damage to nuclear versus mitochondrial DNA (2009), Frederick J. LaRiviere, Adam G. Newman, Megan L. Watts, Sharonda Q. Bradley, Justin E. Juskewitch, Paul G. Greenwood, & Julie T. Millard, Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis, 664, 48-54.
  • 17. Forensic Analysis of Canine DNA Samples in the Undergraduate Biochemistry Laboratory (2009), Tobin M. Carson, Sharonda Q. Bradley, Brenda L. Fekete, Julie T. Millard, and Frederick J. LaRiviere, Journal of Chemical Education 86, 376-378.
  • 16. Adventures in Chemistry (2007) a textbook for non-majors; Houghton-Mifflin Company.
  • 15. Showing the True Face of Chemistry in a Service-Learning Outreach Course (2007) Frederick J. LaRiviere, Lisa M. Miller, & Julie T. Millard, Journal of Chemical Education 84, 1636-1639.
  • 14. DNA Interstrand Cross-Linking by Epichlorohydrin (2007) Keith P. Romano, Adam G. Newman, Rami W. Zahran, & Julie T. Millard, Chemical Research in Toxicology 20, 832-838.
  • 13. The 5'-GNC Site for DNA Interstrand Cross-linking is Conserved for Diepoxybutane Stereoisomers (2006) J. T. Millard, T. C. Hanly, S. Park, & N. Tretyakova, Chemical Research in Toxicology 19, 16-19.
  • 12. Flanking Sequences Modulate Diepoxide and Mustard Cross-Linking Efficiencies at the 5'-GNC Site (2004) G. A. Sawyer, E. D. Frederick, & J. T. Millard, Chemical Research in Toxicology 17, 1057-1063.
  • 11. DNA Interstrand Cross-Linking by a Mycotoxic Diepoxide (2004) J. T. Millard, J. L. Katz, J. Goda, E. D. Frederick, S. E. Pierce, T. J. Speed, & D. M. Thamattoor, Biochimie 86, 419.
  • 10. Identification of Forensic Samples via Mitochondrial DNA in the Undergraduate Biochemistry Laboratory (2003) J. T. Millard & Andre M. Pilon, Journal of Chemical Education 80, 444.
  • 9. Diepoxybutane and Diepoxyoctane Interstrand Cross-Linking of the 5S DNA Nucleosomal Core Particle (2001) J. T. Millard & Erin E. Wilkes, Biochemistry 40, 10677.
  • 8. Cis- and Trans-Diamminedichloroplatinum(II) Interstrand Cross-Linking of a Defined Sequence Nucleosomal Core Particle (2000) J. T. Millard & Erin E. Wilkes, Biochemistry 39, 16046.
  • 7. Molecular Probes of DNA Structure (1999) J. T. Millard, in Comprehensive Natural Products Chemistry, Volume 7: DNA and Aspects of Molecular Biology, E.T. Kool, editor; Elsevier Press, Oxford, pp 81-103.
  • 6. Effect of Nucleosome Structure on DNA Interstrand Cross-Linking Reactions (1998) J.T. Millard, R.J. Spencer, & P.B. Hopkins, Biochemistry 37, 5211.
  • 5. The 5'-GNC Preference for Mustard Cross-Linking is Preserved in a Restriction Fragment (1996) J.T. Millard, N.W. Luedtke, & R.J. Spencer, Anti-Cancer Drug Design 11, 485.
  • 4. DNA Modifying Agents as Tools for Studying Chromatin Structure (1996) J.T. Millard, Biochimie 78, 803.
  • 3. 1,2,5,6-Diepoxyhexane and 1,2,7,8-Diepoxyoctane Cross-Link Duplex DNA at 5'-GNC Sequences (1996) M.J. Yunes, S.E. Charnecki, J.J. Marden, & J.T. Millard, Chemical Research in Toxicology 9, 994.
  • 2. Cytosine Methylation Enhances Mitomycin C Cross-Linking (1993) J.T. Millard & T.M. Beachy, Biochemistry 32, 12850.
  • 1. Diepoxybutane Cross-Links DNA at 5'-GNC Sequences (1993) J.T. Millard & M.M. White, Biochemistry 32, 2120.